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They mimic a natural hormone called glucagon-like peptide-1, which the gut produces after eating
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One of the most significantly upregulated pathways in cardiomyocytes from semaglutide-treated animals was BCAA catabolism: nearly every enzyme in this pathway was significantly upregulated, including the two enzymes required to initiate BCAA catabolism, Bcat2 and the BCKD subunits ( Figure 3C-D )
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